GLP-1 Drug Concerns, Zepbound for Sleep Apnea, and Heatwave Safety
Morning Medical with Dr. Chow
A daily update covering the latest medical & health news from around the world using artificial intelligence. Doctor Chi-Ming Chow is a family physician, general internist, and cardiologist. He is also a Professor of Medicine at the University of Toronto.
Chi-Ming Chow
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GLP-1 Drug Concerns, Zepbound for Sleep Apnea, and Heatwave Safety

E450 • Jun 25, 2026 • 13 mins

In this episode, Dr. Chi-Ming Chow delves into GLP-1 drugs and their potential link to eating disorders, examining study findings and concerns. He discusses challenges with compounded GLP-1 receptor agonists, study limitations, and the need for further research. The episode also covers Health Canada's approval of Zepbound for severe sleep apnea, including its mechanism and clinical trial outcomes. Dr. Chow reviews side effects of GLP-1 drugs like tirzepatide and offers tips for keeping children safe during heatwaves, focusing on air conditioning, car safety, and gender-specific effects. The episode wraps up with strategies for managing women's heat exposure.

Key Points

  • Misuse of GLP-1 drugs among individuals with eating disorders is alarmingly high, with significant risks due to noncommercial compounded products and lack of medical oversight.
  • Health Canada has approved Zepbound, a weight-loss drug aimed at adults with obesity and obstructive sleep apnea, highlighting its potential to significantly reduce breathing interruptions during sleep.
  • Women are more affected by hot weather than men due to higher body fat percentages, hormonal differences, and societal roles, necessitating gender-specific public health strategies for heatwave preparedness.
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